Ovarian cancer remains the eighth leading cause of cancer deaths among American women, and accounts for 3% of all cancers in women.[2] Over a lifetime, 1 in 58 women will develop ovarian cancer, with most cases diagnosed in women 55 or older.[2] If diagnosed and treated while the cancer has not spread outside the ovary, the 5-year survival rate is 90% to 95%. However, only 19% of all ovarian cancers are found at this early stage.[2]
There are three main types of ovarian tumors, and each type responds to different medical approaches. Surgery is usually the initial treatment, followed by chemotherapy. First-line chemotherapy is likely to include "platinum-based" drug combinations. If the cancer should recur, patients often become resistant to these drugs, leading to a second-line choice for chemotherapy.
For some women, recurrence is more disheartening and frightening than the initial diagnosis. But the battle is far from over, with many treatment options to explore. Hycamtin is a chemotherapeutic agent approved by the US Food and Drug Administration (FDA) for the treatment of metastatic carcinoma of the ovary after failure of initial or subsequent chemotherapy.[1]
This site can answer questions you may have about Hycamtin, such as how it works, how it is given, and what side effects may occur. You’ll also find frequently asked questions, including an explanation of ovarian cancer, risk factors, and steps you can take towards prevention. You can learn how to take an active role in your progress and treatment. You may look through aids to help you work with your insurance, along with a helpful guide to support groups.
Remember, no one source can answer all your questions or replace the information provided by your doctors and nurses. This Web site is not intended to replace ongoing communication between you and your health care team.
Important Safety Information
Use of Hycamtin
Hycamtin is used for the treatment of recurrent ovarian cancer.
Reasons Not to Use Hycamtin
Do not use if you have had an allergic reaction to Hycamtin, if you are pregnant, if you are breast-feeding, or if you have low blood counts.
Side Effects
Hycamtin can interfere with your body’s ability to make white and red blood cells. Your doctor may prescribe a supportive therapy to help your body make more blood cells.
Side effects often associated with Hycamtin included nausea (64%), vomiting (45%), diarrhea (32%), hair loss (49%), fatigue (29%), and shortness of breath (22%). Most of these side effects were mild to moderate.
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