Key Facts & Statistics

Causes & Risk Factors

Detection & Diagnosis

Stages of Ovarian Cancer

Treatment Options

Case Studies

Web Resources

Patients/Caregivers – Click Here | E-mail Page
Search

The Hycamtin.com Web site contains links to third-party cancer-related Web sites on the Internet. We hope these will be useful resources for both you and your patients.

American Cancer Society (ACS)

(800) ACS-2345
www.cancer.org
1599 Clifton Road, NE
Atlanta, GA 30329-4251
The ACS is a nationwide, community-based, voluntary health organization dedicated to eliminating cancer as a major health problem.

American College of Medical Genetics

www.acmg.net
Its Web site includes “Genetic Susceptibility to Breast and Ovarian Cancer: Assessment, Counseling and Testing Guidelines” (produced in collaboration with the NYS Department of Health). The guidelines are also available on the NYS Department of Health Web site at www.health.state.ny.us (click on "Health Care Professionals & Patient Safety" and then "Clinical Guidelines").

American College of Obstetricians and Gynecologists

(202) 638-5577
www.acog.org
409 12th Street SW
Washington, DC 20090-6920
The American College of Obstetricians and Gynecologists is a professional organization of physicians who specialize in women’s health care.

American Medical Association (AMA)

(312) 464-5000
www.ama-assn.org/ama/pub/category/3158.html
515 North State Street
Chicago, IL 60610
The AMA provides information on doctors, such as when they were licensed, their specialties, and board certifications. The Directory of Medical Specialists lists qualifications of medical doctors and should be available in medical libraries and the public library.

American Society of Clinical Oncology (ASCO)

(703) 299-0150
www.asco.org
1900 Duke Street, Suite 200
Alexandria, VA 22314
ASCO can provide referrals to gynecologic oncologists in your area.

CancerCare, Inc.

(800) 813-HOPE (Long Island); (212) 712-8400 (New York City)
www.cancercare.org
275 Seventh Avenue
New York, NY 10001
CancerCare, Inc., is a national nonprofit agency dedicated to providing emotional support, information, referral, and practical assistance at no charge to people with cancer and their loved ones.

Cancer Information Service

(800) 4-CANCER
(800) 332-8615 (TTY for deaf and hard-of-hearing callers)
9:00 AM-4:30 PM local time, Monday through Friday
www.cancernet.nci.nih.gov
The Cancer Information Service is a national information and education network sponsored by the National Cancer Institute. Information is available in English and Spanish.

Cancer Risk Assessment Survey

Women’s Cancer Network
www.wcn.org/interior.cfm?diseaseid=13&featureid=3
The Cancer Risk Assessment Survey is an online, interactive cancer risk assessment survey that helps identify risk level for the gynecologic cancers.

CanSurmount

(800) ACS-2345
CanSurmount, an ACS program, provides short-term visitor programs for cancer patients and family members in the hospital and/or at the home for support and encouragement.

Centers for Disease Control and Prevention

Division of Cancer Prevention & Control
(800) CDC-INFO
www.cdc.gov/cancer/index.htm
4770 Buford Highway NE, MS K64
Atlanta, GA 30341

Ovarian Cancer Control Initiative

(404) 639-3311
www.cdc.gov/cancer/ovarian/
1600 Clifton Road
Atlanta, GA 30333
The Initiative enhances the limited knowledge base around ovarian cancer by initiating projects with partners, academic and medical colleagues, and advocacy groups to identify factors related to early disease detection and treatment.

Continental Care Force

(281) 261-6626
Provides free air transportation to medical patients with financial need.

Conversations! The International Newsletter for Those Fighting Ovarian Cancer

(806) 355-2565
www.ovarian-news.com
PO Box 7948
Amarillo, TX 79114-7948
This monthly newsletter, written by an ovarian cancer survivor, reports on treatment options, trials, coping skills, and early-detection strategies. Conversations! offers humor and an upbeat tone. A networking service to match women in similar circumstances is available.

Coping With Cancer Magazine

(615) 790-2400
PO Box 682268
Franklin, TN 37068-2268
This is a bimonthly magazine for people who have been touched by cancer. Issues include patient education articles by health care professionals.

Corporate Angel Network

(914) 328-1313
www.corpangelnetwork.org
One Loop Road
White Plains, NY 10604
Corporate Angel Network is a nonprofit organization that finds space on corporate jets, at no charge to the patient, for cancer patients and one attendant/family member needing transportation for treatment, consultation, and checkups.

Department of Defense Ovarian Cancer Research Program

(Congressionally Directed Medical Research Programs)
(301) 619-7071
http://cdmrp.army.mil/ocrp/default.htm

FORCE (Facing Our Risk of Cancer Empowered, Inc)

(954) 255-8732
www.facingourrisk.org/
16057 Tampa Palms Boulevard West, PMB #373
Tampa, FL 33647
This is an organization for those at increased risk of breast/ovarian cancer due to positive family history and/or BRCA mutations. Patients can gather information and support, communicate with others, learn through librarian-selected links, and locate specialists.

Gilda Radner Ovarian Cancer Familial Registry

(800) OVARIAN
www.ovariancancer.com
Roswell Park Cancer Institute
Elm and Carlton Streets
Buffalo, NY 14263
The Registry tracks families with a history of ovarian cancer, and offers a help-line, education, information, and peer support for women with high risk (family history) of ovarian cancer.

Gilda’s Club Worldwide

(888) GILDA-4-U
www.gildasclub.org
322 Eighth Avenue, Suite 1402
New York, NY 10001
Gilda’s Club provides a place where people living with cancer, their families, and friends can join others to build social and emotional support as a supplement to medical care.

Gynecologic Cancer Foundation (GCF)

(800) 444-4441
www.thegcf.org
230 West Monroe, Suite 2528
Chicago, IL 60606
The GCF is a not-for-profit fundraising organization established by the Society of Gynecologic Oncologists (SGO) to support ovarian cancer research, the training of cancer specialists in laboratory research, and a variety of programs for patient education and public awareness of gynecologic cancers. Callers will be able to obtain a list of nearby specialists in gynecologic oncology, a nationwide directory of all SGO members, and informational literature.

Hereditary Cancer Institute

(402) 280-2942
Henry Lynch, MD
Creighton University School of Medicine
2500 California Plaza
Omaha, NE 68178
The Hereditary Cancer Institute provides free cancer-risk information and other forms of genetic counseling.

Lance Armstrong Foundation

(512) 236-8820
www.livestrong.org
PO Box 161150
Austin, TX 78716-1150
The Foundation focuses on cancer survivorship issues for people living with, through, and beyond cancer.

Look Good...Feel Better

(800) 395-LOOK
www.lookgoodfeelbetter.org
CTFA Foundation
1101 17th Street NW
Washington, DC 20036
Co-sponsored by the Cosmetic, Toiletry and Fragrance Association, the American Cancer Society, and the National Cosmetology Association, this public service program teaches women ways to cope with appearance-related side effects of cancer treatment.

Marsha Rivkin Center for Ovarian Cancer Research

(800) 328-1124
www.marsharivkin.org
1221 Madison Street, Suite 1401
Seattle, WA 98104
The Marsha Rivkin Center for Ovarian Cancer Research promotes prevention, research, detection, and awareness.

National Cancer Institute (NCI)

(800) 4-CANCER
www.cancernet.nci.nih.gov
The NCI provides a nationwide telephone service for cancer patients and their families and friends, the public, and health care professionals that answers questions and sends booklets and information about cancer.

National Coalition for Cancer Survivorship

(877) NCCS-YES
www.cansearch.org
1010 Wayne Avenue, Suite 770
Silver Spring, MD 20910
The NCCS raises awareness of cancer survivorship through its publications, quarterly newsletters, education to eliminate the stigma of cancer, and advocacy for insurance, employment, and legal rights for people with cancer.

National Hospice and Palliative Care Organization

(800) 646-6460
www.nhpco.org
1700 Diagonal Road, Suite 625
Alexandria, VA 22314
The National Hospice Organization is an association of groups that provide hospice care. Founded in 1978 to promote and maintain quality hospice care and encourage support for patients and family members, this organization can provide information on local hospices.

National Ovarian Cancer Coalition (NOCC)

(888) OVARIAN
www.ovarian.org
500 NE Spanish River Blvd., Suite 8
Boca Raton, FL 33431
The NOCC raises awareness about ovarian cancer and promotes education about ovarian cancer throughout the general population and the medical community. The NOCC has chapters throughout the country.

The Newsletter of the Gilda Radner Familial Ovarian Cancer Registry

(800) OVARIAN
www.ovariancancer.com/newsletter.asp
Roswell Park Cancer Institute
Elm and Carlton Streets
Buffalo, NY 14263-0001

NYS Ovarian Cancer Information Program

(518) 474-1222
www.health.state.ny.us/diseases/cancer/ovarian/overview.htm
NYS Department of Health
Bureau of Chronic Disease Services
Riverview Center
150 Broadway, 3rd Floor West
Albany, NY 12204
This program promotes a public health approach to ovarian cancer awareness and education.

Office on Women’s Health

Department of Health and Human Services
(800) 994-9662
www.4woman.gov

Oncolink: The University of Pennsylvania Cancer Center Online Resource

www.oncolink.upenn.edu
Oncolink is a comprehensive information source, including links to online discussion groups.

Ovarian Cancer National Alliance

(202) 331-1332
www.ovariancancer.org
910 17th Street NW, Suite 1190
Washington, DC 20006
The Ovarian Cancer National Alliance is a national umbrella organization that works to increase public and professional understanding of ovarian cancer, and to advocate for more effective diagnostics, treatments, and a cure. Members include survivors and family members, local and national organizations, and health care providers. Materials include awareness information and national policy issue papers. The Alliance sponsors an annual Advocacy Conference.

Ovarian Cancer Research Fund, Inc. (OCRF)

(800) 873-9569
www.ocrf.org
14 Pennsylvania Plaza, Suite 1400
New York, NY 10122
The OCRF is devoted to the formation of early diagnostic treatment programs and research toward the ultimate conquest of ovarian cancer. As OCRF strives to find a cure, it also provides educational outreach programs and public awareness projects, including videos about ovarian cancer and resource materials.

Ovarian Plus International: Gynecologic Cancer Prevention Quarterly

(703) 644-3162
www.monitor.net/ovarian
The newsletter has timely information about international research, diagnosis, and treatments for ovarian cancer and other gynecologic cancers. It targets risk reduction, screening, early detection, psychosocial and policy issues, and addresses current events in the ovarian cancer community.

Ovarian Problems Discussion List

www.acor.org
The Ovarian Problems Discussion List is an e-mail support group. To subscribe, browse through the many cancer lists there.

SHARE: Self-Help for Women with Breast or Ovarian Cancer

(866) 891-2392
www.sharecancersupport.org
1501 Broadway, Suite 704A
New York, NY 10036
SHARE is a not-for-profit organization providing information hotlines for breast and ovarian cancer in English and Spanish; peer led support groups; and wellness, education, and advocacy programs. SHARE contributes to awareness regarding research, prevention, and early detection.

Society of Gynecologic Nurse Oncologists (SGNO)

(314) 644-4900
www.sgno.org
1610 South Big Bend Boulevard
St. Louis, MO 63117

Society of Gynecologic Oncologists (SGO)

(312) 235-4060
www.sgo.org
230 West Monroe, Suite 710
Chicago, IL 60606
The SGO provides referrals to gynecologic oncologists.

Talking it Ovar

(888) OVARIAN
Talking it Ovar is a telephone support program for those dealing with a diagnosis of ovarian cancer, sponsored by the National Ovarian Cancer Coalition, Inc.

The Wellness Community

(888) 793-WELL
www.thewellnesscommunity.org
919 18th Street NW, Suite 54
Washington, DC 20006
The Wellness Community provides free psychosocial support to people fighting to recover from cancer as an adjunct to conventional medical treatment.

Women’s Cancer Network

www.wcn.org
The Women’s Cancer Network is an interactive Internet site that offers understandable medical information about gynecologic cancers, treatment options, and experimental programs. By answering specific questions a woman will be told her risk for developing specific cancers such as gynecologic, breast, and colon cancers, and how to change those risks.

Disclaimer

These sites are not part of Hycamtin.com, a GlaxoSmithKline Web site. The content and materials in these third-party Web sites are not produced or endorsed by GlaxoSmithKline.

Some of these third-party Web sites may refer to uses of our products that are not recommended by GlaxoSmithKline. You should always consult with your physician or health care professional before using any GlaxoSmithKline prescription product.

Important Safety Information

Contraindications

Hycamtin is contraindicated in patients who have a history of hypersensitivity reactions to topotecan or to any of its ingredients. Hycamtin should not be used in patients who are pregnant or breast-feeding, or those with severe bone marrow depression.

Warnings

Hycamtin should be used only in patients with adequate bone marrow reserves, including baseline neutrophil counts of at least 1,500 cells/mm³ and platelet counts of at least 100,000/mm³. Frequent monitoring of blood counts should be instituted during treatment with Hycamtin.

Patients should not be treated with subsequent courses of Hycamtin until neutrophils recover to >1,000 cells/mm³, platelets recover to >100,000 cells/mm³, and hemoglobin levels recover to 9.0 g/dL (with transfusion if necessary).

Hycamtin may cause fetal harm when administered to a pregnant woman. Women of childbearing potential should be advised to avoid becoming pregnant during therapy with Hycamtin.

Drug Interactions

Concomitant administration of G-CSF can prolong the duration of neutropenia, so if G-CSF is to be used, it should not be initiated until day 6 of the course of therapy, 24 hours after completion of treatment with Hycamtin.

Myelosuppression was more severe when Hycamtin was given in combination with cisplatin in phase I studies. In a reported study on concomitant administration of cisplatin 50 mg/m² and Hycamtin at a dose of 1.25 mg/m²/day x 5 days, 1 of 3 patients had severe neutropenia for 12 days, and a second patient died with neutropenic sepsis. There are no adequate data to define a safe and effective regimen for Hycamtin and cisplatin in combination.

Adverse Events

Frequently reported nonhematologic adverse events associated with use of Hycamtin included nausea (64%), vomiting (45%), diarrhea (32%), alopecia (49%), fatigue (29%), and dyspnea (22%). Most nonhematologic toxicities were grade 1 or 2.

Home | Prescribing Information for Hycamtin

This site is intended for US healthcare professionals only.
© 1997-2008 GlaxoSmithKline. All Rights Reserved.
Legal Notices | Privacy Statement | Medicine Savings | Contact Us